At the suggestion of frequent commenter Mike from Norwell, I’m adding a box for those who wish to donate to relief efforts for victims of the Haitian earthquake.
Rather than link to a long list of charities, which you can find pretty much anywhere (I recommend the Boston Globe’s list), I’m designating a fund set up by my religious denomination. It’s a joint effort of the Unitarian Universalist Association and the Unitarian Universalist Service Committee.
Media Nation 
Dan, good choice for a charity, and I’ll add this link to the WSJ (with some words of advise in the article about what to do – cash is king in a catastrophe – drives for goods/physical donations are well intentioned but won’t get there)
http://blogs.wsj.com/dispatch/2010/01/13/where-to-donate-and-how/